Thyroglobulin (TG) Mouse Monoclonal Antibody [Clone ID: OTI11F8]
USD 867.00
Specifications
Product Data | |
Clone Name | OTI11F8 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 20-358 of human TG (NP_003226) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | thyroglobulin |
Database Link | |
Background | Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009] |
Synonyms | AITD3; TGN |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Autoimmune thyroid disease |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF803992 | Carrier-free (glycerol/BSA-free) TG mouse monoclonal antibody, clone OTI11F8 (formerly 11F8) |
USD 600.00 |
|
TA803992 | TG mouse monoclonal antibody, clone OTI11F8 (formerly 11F8) |
USD 447.00 |
|
TA803992AM | TG mouse monoclonal antibody, clone OTI11F8 (formerly 11F8), Biotinylated |
USD 509.00 |
|
TA803992BM | TG mouse monoclonal antibody, clone OTI11F8 (formerly 11F8), HRP conjugated |
USD 509.00 |
{0} Product Review(s)
Be the first one to submit a review