ALK Rat Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1D9]
USD 867.00
USD 665.00
Specifications
Product Data | |
Clone Name | OTI1D9 |
Applications | LMNX, WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Rat |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1060-1620 of human ALK (NP_004295)produced in SF9 Cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 176.3 kDa |
Gene Name | anaplastic lymphoma receptor tyrosine kinase |
Database Link | |
Background | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011] |
Synonyms | CD246; NBLST3 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF801141 | Carrier-free (BSA/glycerol-free) ALK rat monoclonal antibody, clone OTI1D9 (formerly 1D9) |
USD 600.00 |
|
TA801141 | ALK rat monoclonal antibody, clone OTI1D9 (formerly 1D9) |
USD 447.00 |
|
TA801141BM | ALK rat monoclonal antibody,clone 1D9, HRP conjugated |
USD 509.00 |
|
TA801141S | ALK rat monoclonal antibody, clone OTI1D9 (formerly 1D9) |
USD 200.00 |
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