SPHK1 Mouse Monoclonal Antibody [Clone ID: OTI1A6]
CAT#: TA507215
SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
Size: 30 ul
Formulation: Carrier-Free
USD 867.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI1A6 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:400~4000, IHC 1:150, IF 1:100 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human SPHK1(NP_068807) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 43.8 kDa |
Gene Name | sphingosine kinase 1 |
Database Link | |
Background | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Synonyms | SPHK |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF507215 | Carrier-free (BSA/glycerol-free) SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) |
USD 600.00 |
|
TA507215AM | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), Biotinylated |
USD 509.00 |
|
TA507215BM | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), HRP conjugated |
USD 509.00 |
|
TA507215S | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) |
USD 200.00 |
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