IL1 beta (IL1B) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A7]
CAT#: TA506440AM
IL1B mouse monoclonal antibody,clone 1A7, Biotinylated
Conjugation: Unconjugated HRP
USD 867.00
Specifications
Product Data | |
Clone Name | OTI1A7 |
Applications | WB |
Recommended Dilution | WB 1:4000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 30.6 kDa |
Gene Name | interleukin 1 beta |
Database Link | |
Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
Synonyms | IL-1; IL1-BETA; IL1F2 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF506440 | Carrier-free (BSA/glycerol-free) IL1B mouse monoclonal antibody, clone OTI1A7 (formerly 1A7) |
USD 600.00 |
|
TA506440 | IL1B mouse monoclonal antibody, clone OTI1A7 (formerly 1A7) |
USD 447.00 |
|
TA506440BM | IL1B mouse monoclonal antibody,clone 1A7, HRP conjugated |
USD 509.00 |
|
TA506440S | IL1B mouse monoclonal antibody, clone OTI1A7 (formerly 1A7) |
USD 200.00 |
{0} Product Review(s)
Be the first one to submit a review