PIK3R5 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6C5]
CAT#: TA505826AM
PIK3R5 mouse monoclonal antibody,clone 6C5, Biotinylated
Conjugation: Unconjugated HRP
Specifications
Product Data | |
Clone Name | OTI6C5 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PIK3R5(NP_055123) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 97.2 kDa |
Gene Name | phosphoinositide-3-kinase regulatory subunit 5 |
Database Link | |
Background | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011] |
Synonyms | F730038I15Rik; FOAP-2; p101; P101-PI3K |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF505826 | Carrier-free (BSA/glycerol-free) PIK3R5 mouse monoclonal antibody, clone OTI6C5 (formerly 6C5) |
USD 600.00 |
|
TA505826 | PIK3R5 mouse monoclonal antibody, clone OTI6C5 (formerly 6C5) |
USD 447.00 |
|
TA505826BM | PIK3R5 mouse monoclonal antibody,clone 6C5, HRP conjugated |
USD 509.00 |
|
TA505826S | PIK3R5 mouse monoclonal antibody, clone OTI6C5 (formerly 6C5) |
USD 200.00 |
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