Pyruvate Kinase (PKLR) Mouse Monoclonal Antibody [Clone ID: OTI1F3]
USD 867.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI1F3 |
Applications | FC, IF, WB |
Recommended Dilution | WB 1:2000, IF 1:100, FLOW 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PKLR (NP_000289) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 61.6 kDa |
Gene Name | pyruvate kinase L/R |
Database Link | |
Background | The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | PK1; PKL; PKR; PKRL; RPK |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Glycolysis / Gluconeogenesis, Insulin signaling pathway, Maturity onset diabetes of the young, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF501412 | Carrier-free (BSA/glycerol-free) PKLR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) |
USD 600.00 |
|
TA501412 | Anti-PKLR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) |
USD 224.00 |
|
TA501412AM | Anti-PKLR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3), Biotinylated |
USD 509.00 |
|
TA501412BM | Anti-PKLR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3), HRP conjugated |
USD 509.00 |
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