Amyloid Precursor Protein (APP) Mouse Monoclonal Antibody [Clone ID: OTI5F1]
CAT#: TA500991
APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5F1 (formerly 5F1)
Size: 30 ul
Formulation: Carrier-Free
USD 867.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI5F1 |
Applications | IF, WB |
Recommended Dilution | WB 1:2000, IF 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human APP (NP_000475) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.8 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 87.0 kDa |
Gene Name | amyloid beta precursor protein |
Database Link | |
Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
Synonyms | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Alzheimer's disease |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500991 | Carrier-free (BSA/glycerol-free) APP mouse monoclonal antibody, clone OTI5F1 (formerly 5F1) |
USD 600.00 |
|
TA500991AM | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5F1 (formerly 5F1), Biotinylated |
USD 509.00 |
|
TA500991BM | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5F1 (formerly 5F1), HRP conjugated |
USD 509.00 |
|
TA500991S | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI5F1 (formerly 5F1) |
USD 200.00 |
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