MUC16 Mouse Monoclonal Antibody [Clone ID: 20000]

CAT#: TA399870

Anti-CA125 [20E3], Mouse IgG2b, kappa

Specifications

Product Data

• Clone Name: 20000
• Applications: ELISA, IHC, WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b, kappa
• Clonality: Monoclonal
• Immunogen: The original antibody was generated by immunizing mice with recombinant protein CA125.
• Specificity: The original antibody is specific for CA125. CA125 is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. This antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer.
  
  The antibody 20E3 and the commercial antibody TA347 were used to stain ovarian slurry adenocarcinoma and ovarian mucous adenocarcinoma in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 20E3 was higher than the commercial antibody (CN113061186A).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
• Database Link:
  UniProt ID Q8WXI7
• Synonyms: CA-125; CGMCC NO 20773; MUC-16; Mucin-16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125; TA347