CD11b (ITGAM) Mouse Polyclonal Antibody

CAT#: TA392965

CD11B (L1) monoclonal antibody

Product Images

Western blot (WB) analysis of CD11B (L1) mAb at 1:500 dilution Lane1:Myla2059 whole cell lysate(30ug) Lane2:HuT78 whole cell lysate(30ug) Lane3:K562 whole cell lysate(30ug) Lane4:The Spleen tissue lysate of Rat(40ug) Lane5:RAW264.7 whole cell lysate(40ug) Lane6:THP-1 whole cell lysate(40ug)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant Human CD11B (630aa-1104aa).
• Specificity: CD11B (L1) mAb detects endogenous levels of CD11B protein.
• Formulation: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 170 kDa
• Gene Name: integrin subunit alpha M
• Database Link:
  Entrez Gene 3684 Human
  UniProt ID P11215
• Background: Integrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
• Synonyms: CD11 antigen-like family member B; CD11B; CD11b; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; CR-3α; CR3A; CR3α; Integrin alpha-M; Integrin αM; ITGAM; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor
• Note: For research use only, not for use in diagnostic procedure.