RSK1 p90 (RPS6KA1) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:1000~1:2000 IHC: 1:50~1:200 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic phosphopeptide derived from human Rsk-1 around the phosphorylation site of Serine 380. |
Specificity | p-Rsk-1 (S380) polyclonal antibody detects endogenous levels of Rsk-1 protein only when phosphorylated at Ser380. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Stability | 1 year |
Predicted Protein Size | ~ 90 kDa |
Gene Name | ribosomal protein S6 kinase A1 |
Database Link | |
Background | The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. |
Synonyms | 90 kDa ribosomal protein S6 kinase 1; MAPK-activated protein kinase 1a; MAPKAPK-1a; MAPKAPK1A; MAPKAP kinase 1a; MAP kinase-activated protein kinase 1a; p90-RSK 1; p90RSK1; p90S6K; Ribosomal protein S6 kinase alpha-1; Ribosomal S6 kinase 1; RPS6KA1; RSK-1; RSK1; S6K-alpha-1; S6K-α1; S6K α1; S6Kα1 |
Note | For research use only, not for use in diagnostic procedure. |
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