IL5RA Rabbit Polyclonal Antibody

CAT#: TA392461

CD125 polyclonal antibody

Product Images

Western blot (WB) analysis of CD125 polyclonal antibody at 1:2000 dilution Lane1:EC9706 cell membrane lysate(25ug) Lane2:MCF-7 cell membrane lysate(25ug)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:2000~1:5000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CD125.
• Specificity: CD125 polyclonal antibody detects endogenous levels of CD125 protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 60 kDa
• Gene Name: interleukin 5 receptor subunit alpha
• Database Link:
  Entrez Gene 3568 Human
  UniProt ID Q01344
• Background: Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils .Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5.In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway .
• Synonyms: CD125; CDw125; IL-5 receptor subunit alpha; IL-5R-alpha; IL-5RA; IL-5R subunit alpha; Interleukin-5 receptor subunit alpha
• Note: For research use only, not for use in diagnostic procedure.