Nectin 2 (NECTIN2) Rabbit Polyclonal Antibody

CAT#: TA392460

CD112/NECTIN2 polyclonal antibody

Product Images

Western blot (WB) analysis of CD112/NECTIN2 polyclonal antibody at 1:2000 dilution Lane1:CT-26 whole cell lysate(30ug) Lane2:H1792 whole cell lysate(20ug) Lane3:HEK293T whole cell lysate(20ug)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:2000~1:5000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CD112/NECTIN2.
• Specificity: CD112/NECTIN2 polyclonal antibody detects endogenous levels of CD112/NECTIN2 protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 60-70 kDa
• Gene Name: nectin cell adhesion molecule 2
• Database Link:
  Entrez Gene 5819 Human
  UniProt ID Q92692
• Background: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive .Probable cell adhesion protein .
• Synonyms: CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin-2; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2
• Note: For research use only, not for use in diagnostic procedure.