ATF3 Rabbit Polyclonal Antibody
Frequently bought together (1)
Other products for "ATF3"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 1:1000~1:2000 IHC: 1:50~1:200 |
Reactivities | Human, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to Human ATF3. |
Specificity | ATF-3 (N159) polyclonal antibody detects endogenous levels of ATF-3 protein. |
Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Stability | 1 year |
Predicted Protein Size | ~ 24 kDa |
Gene Name | activating transcription factor 3 |
Database Link | |
Background | Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene. |
Synonyms | Activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; Cyclic AMP-dependent transcription factor ATF-3 |
Note | For research use only, not for use in diagnostic procedure. |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.