DR5 (TNFRSF10B) Rabbit Polyclonal Antibody

CAT#: TA392394

CD262 polyclonal antibody

Product Images

Western blot (WB) analysis of CD262 polyclonal antibody at 1:1000 dilution Lane1:Hela whole cell lysate(30ug) Lane2:A549 whole cell lysate(30ug) Lane3:The Heart tissue lysate of Mouse(30ug) Lane4:The Heart tissue lysate of Rat(30ug)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000~1:2000
• Reactivities: Human, Rat, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CD262.
• Specificity: CD262 polyclonal antibody detects endogenous levels of CD262protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 55 kDa
• Gene Name: tumor necrosis factor receptor superfamily member 10b
• Database Link:
  Entrez Gene 8795 Human
  UniProt ID O14763
• Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
• Synonyms: Death receptor 5; DR5, KILLER, TRAILR2, TRICK2, ZTNFR9; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL-R2; TRAIL receptor 2; Tumor necrosis factor receptor superfamily member 10B; UNQ160/PRO186
• Note: For research use only, not for use in diagnostic procedure.