Anti-IL5RA antibody(DMC393), IgG1 Chimeric mAb

CAT#: TA389523

Anti-IL5RA antibody(DMC393), IgG1 Chimeric mAb

Specifications

Product Data

• Applications: FC
• Recommended Dilution: Flow Cyt 1:100
• Reactivities: Human
• Host: Rabbit
• Clonality: Monoclonal
• Formulation: 1XPBS
• Concentration: Lot specific
• Purification: Purified from cell culture supernatant by affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
• Stability: 12 months from date of despatch
• Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
• Synonyms: IL5Ra,CD125,IL-5 R alpha