Polysialic acid Mouse Monoclonal Antibody [Clone ID: 735]
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Specifications
Product Data | |
Clone Name | 735 |
Applications | FC, IHC, IP |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a, kappa |
Clonality | Monoclonal |
Immunogen | Homopolymers of α2,8-linked sialic acid of Escherichia coli K1. |
Specificity | Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of α2,8-linked sialic acid of Escherichia coli K1. This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al. 1990). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al. 2006). |
Formulation | PBS with 0.02% Proclin 300. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
Stability | 3 years from dispatch. |
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