CD299 (CLEC4M) Mouse Monoclonal Antibody [Clone ID: 160000000]

CAT#: TA385701

Recombinant Anti-DC-SIGNR (Clone 16E7)

Specifications

Product Data

• Clone Name: 160000000
• Applications: FC, IHC
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: CD299
• Specificity: Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: C-type lectin domain family 4 member M
• Database Link:
  Entrez Gene 10332 Human
  UniProt ID Q9H2X3
• Synonyms: CD209L; CD209L1; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN; MGC47866; MGC129964