IL17RC Rabbit Polyclonal Antibody
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Other products for "IL17RC"
Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | WB: 1/500-1/2000 ELISA: 1/20000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770 |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | Observed MW (kDa):70 |
Database Link | |
Background | Swiss-Prot Acc.Q8NAC3.Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495). |
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