EWSR1 Rabbit Monoclonal Antibody [Clone ID: R09-3A7]

CAT#: TA384193

EWSR1 Rabbit monoclonal Antibody

Product Images

Western blot detection of EWSR1 in Rat brain lysates using EWSR1 antibody.Predicted band size:69kDa.Observed band size:85kDa.

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  Western blot detection of EWSR1 in MCF7,3T3,Hela cell lysates using EWSR1 Rabbit mAb(1:1000 diluted).Predicted band size:69KDa.Observed band size:85KDa.

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  Immunocytochemistry of EWSR1(green) in Hela cells using EWSR1 Rabbit mAb at dilution 1/50, and DAPI(blue)

Specifications

Product Data

• Clone Name: R09-3A7
• Applications: IF, WB
• Recommended Dilution: WB: 1/2000-1/10000
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human EWSR1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 69 kDa; Observed MW: 85 kDa
• Gene Name: EWS RNA binding protein 1
• Database Link:
  Entrez Gene 2130 Human
  UniProt ID Q01844
• Background: Swiss-Prot Acc.Q01844.Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.SitesFeature keyPosition(s)Description
• Synonyms: bK984G1.4; EWS