CIRBP Rabbit Monoclonal Antibody [Clone ID: R01-4B2]

CAT#: TA384002

CIRBP Rabbit monoclonal Antibody

Product Images

Western blot detection of CIRBP in Hela cell lysates using CIRBP Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.

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  Immunohistochemistry of CIRBP in paraffin-embedded Human breast cancer tissue using CIRBP Rabbit mAb at dilution 1/50

Specifications

Product Data

• Clone Name: R01-4B2
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/200
  IP: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human CIRBP
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 19 kDa; Observed MW: 19 kDa
• Gene Name: cold inducible RNA binding protein
• Database Link:
  Entrez Gene 1153 Human
  UniProt ID Q14011
• Background: Swiss-Prot Acc.Q14011.Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.
• Synonyms: A18HNRNP; CIRP