RbAp46 (RBBP7) Rabbit Polyclonal Antibody
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Other products for "RBBP7"
Specifications
Product Data | |
Applications | ChIP, ICC/IF, IHC, WB |
Recommended Dilution | WB,1:500 - 1:2000 IF,1:50 - 1:200 ChIP,1:50 - 1:200 |
Reactivities | Human, Rat, Mouse |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RBBP7 (NP_002884.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 47kDa/52kDa |
Gene Name | RB binding protein 7, chromatin remodeling factor |
Database Link | |
Background | This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. |
Synonyms | MGC138867; MGC138868; RbAp46; RBBP-7 |
Reference Data |
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