Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Rabbit Polyclonal Antibody

CAT#: TA377235

HSD17B4 Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using HSD17B4 antibody (TA377235) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human HSD17B4 (NP_000405.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 77kDa/79kDa/83kDa
• Gene Name: hydroxysteroid (17-beta) dehydrogenase 4
• Database Link:
  Entrez Gene 3295 Human
  UniProt ID P51659
• Background: The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Synonyms: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest; beta-keto-reductase; DBP; EDH17B4; MFE-2; SDR8C1