FUNDC2 Rabbit Polyclonal Antibody

CAT#: TA370499

FUNDC2 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA370499 (FUNDC2 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA370499 (FUNDC2 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370499 (FUNDC2 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370499 (FUNDC2 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-300
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human FUNDC2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: FUN14 domain containing 2
• Database Link:
  Entrez Gene 65991 Human
  UniProt ID Q9BWH2
• Background: FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
• Synonyms: DC44; FLJ33773; HCBP6; HCC-3; HCC3; MGC2495; MGC131676; PD03104