FCP1 (CTDP1) Rabbit Polyclonal Antibody

CAT#: TA368318

CTDP1 rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: HEPG2 cell lysate Primary antibody: TA368318 (CTDP1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 minutes

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA368318 (CTDP1 Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA368318 (CTDP1 Antibody) at dilution 1/55, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA368318 (CTDP1 Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA368318 (CTDP1 Antibody) at dilution 1/55, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HEPG2 cell lysate
  IHC: 50-300
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CTDP1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 104 kDa
• Gene Name: CTD phosphatase subunit 1
• Database Link:
  Entrez Gene 9150 Human
  UniProt ID Q9Y5B0
• Background: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: CCFDN; FCP1