FAAP24 Rabbit Polyclonal Antibody
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Other products for "FAAP24"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 30-150 Positive control: Human liver cancer Predicted cell location: Cytoplasm or Nucleus |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human FAAP24 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Gene Name | Fanconi anemia core complex associated protein 24 |
Database Link | |
Background | Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. |
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