EPS15 Rabbit Polyclonal Antibody

CAT#: TA368267

EPS15 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA368267 (EPS15 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA368267 (EPS15 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA368267 (EPS15 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA368267 (EPS15 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-300
  Positive control: Human cervical cancer
  Predicted cell location: Cell membrane and Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human EPS15
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: epidermal growth factor receptor pathway substrate 15
• Database Link:
  Entrez Gene 2060 Human
  UniProt ID P42566
• Background: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Synonyms: AF-1P; AF1P; MLLT5