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ARHGEF11 Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm |
| Reactivities | Human, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARHGEF11 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Gene Name | Rho guanine nucleotide exchange factor 11 |
| Database Link | |
| Background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. |
| Synonyms | DKFZp667F1223; GTRAP48; KIAA0380; PDZ-RHOGEF |
| Reference Data | |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.