GNS Rabbit Polyclonal Antibody

CAT#: TA366562

GNS rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA366562 (GNS Antibody) at dilution 1/80 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA366562 (GNS Antibody) at dilution 1/80, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colorectal cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human GNS
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: glucosamine (N-acetyl)-6-sulfatase
• Database Link:
  Entrez Gene 2799 Human
  UniProt ID P15586
• Background: The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
• Synonyms: G6S; Glucosamine-6-sulfatase; MGC21274; N-acetylglucosamine-6-sulfatase