CD5 Mouse Monoclonal Antibody [Clone ID: CRIS-1]
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Specifications
Product Data | |
Clone Name | CRIS-1 |
Applications | IHC |
Recommended Dilution | Tested for immunohistochemistry (IHC); has been described to work in FACS. Approximate working dilution for IHC: Frozen sections: ≤0.1µg/ml (1:2000) Paraffin sections: not tested Optimal dilutions should be determined by the end user. Suggested positive control: Human tonsil |
Reactivities | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Stimulated human leukocytes. |
Specificity | Human: CD5
Other: not tested. Epitope: The antigen is CD5. The epitope has not been further characterized. Distribution: Isolated cells: the antibody stains approximately 50-90% of human peripheral blood mononuclear cells in flow cytometry. Tissue sections: the antibody reacts with the interfollicular area and mantle zone in tonsil. |
Formulation | Affinity purified, lyophilized Reconstitute by adding 0.5ml distilled water. This stock solution contains 0.2mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative. |
Concentration | N/A |
Conjugation | Unconjugated |
Storage | Original vial: 1 year at 4° - 8°C. Stock solution or aliquots thereof: 1 year at -20°C. Avoid repeated thawing and freezing. |
Gene Name | CD5 molecule |
Database Link | |
Background | Monoclonal antibody CRIS-1 recognizes the human CD5 antigen. CD5 is expressed at low density early on thymocytes and at high density on all mature T lymphocytes. CD5 is expressed at low density on a small subset of mature B lymphocytes (B1a cells) which is expanded during fetal life and in several autoimmune disorders as well as in some B cell- derived lymphoproliferative disorders (chronic lymphocytic leukemia, CLL). CD5 is a glycoprotein monomer of 67kD which belongs to the scavenger receptor cysteine- rich (SRCR) family of extracellular domain-like structures and possesses a large cytoplasmic domain suitable for signal transduction |
Synonyms | LEU1; T1 |
Reference Data |
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