ELAC2 Rabbit Polyclonal Antibody

CAT#: TA362073

ELAC2 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: ELAC2 Sample Tissue: Human HepG2 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ELAC2
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 86 kDa
• Gene Name: elaC ribonuclease Z 2
• Database Link:
  NP_001159434.1
  Entrez Gene 60528 Human
  UniProt ID Q9BQ52-4
• Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Â
• Synonyms: ELC2; FLJ10530; FLJ36693; FLJ42848; HPC2

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency