PFKFB2 Rabbit Polyclonal Antibody

CAT#: TA360176

PFKFB2 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: PFKFB2 Sample Tissue: Human COLO205 Whole Cell Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PFKFB2
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 58 kDa
• Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
• Database Link:
  NP_001018063.1
  Entrez Gene 5208 Human
  UniProt ID O60825
• Background: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatas; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphata; DKFZp781D2217; MGC138308; MGC138310; PFK-2/FBPase-2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism