FVT1 (KDSR) Rabbit Polyclonal Antibody

CAT#: TA356467

KDSR Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: KDSR Sample Type: PANC1 Whole cell lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human KDSR
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 29kDa
• Gene Name: 3-ketodihydrosphingosine reductase
• Database Link:
  NP_002026.1
  Entrez Gene 2531 Human
  UniProt ID B4DMX0
• Background: The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
• Synonyms: DHSR; FLJ36555; FLJ92680; FVT-1; FVT1; SDR35C1

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism