AIRE Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human autoimmune regulator (AIRE), transcript variant AIRE-1, 20 µg
USD 867.00
Transient overexpression lysate of autoimmune regulator (AIRE), transcript variant AIRE-2
USD 436.00
Other products for "AIRE"
Specifications
Product Data | |
Applications | WB |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE |
Specificity | Expected reactivity: Cow, Dog, Horse, Human, Pig, Rat Homology: Cow: 79%; Dog: 92%; Horse: 86%; Human: 100%; Pig: 93%; Rat: 79% |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 58kDa |
Gene Name | autoimmune regulator |
Database Link | |
Background | The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |
Synonyms | AIRE1; APECED; APS1; APSI; OTTHUMP00000109529; PGA1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Primary immunodeficiency, Ubiquitin mediated proteolysis |
Documents
Product Manuals |
FAQs |
SDS |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.