IL6 Mouse Monoclonal Antibody [Clone ID: 10C12]

CAT#: TA355306

Interleukin 6 Mouse Monoclonal Antibody

Product Images

Human colon: immunohistochemical staining for Interleukin 6. Note cytoplasmic staining of a proportion of lymphoid cells. Interleukin 6: clone 10C12

Specifications

Product Data

• Clone Name: 10C12
• Applications: IHC
• Recommended Dilution: 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: A prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule
• Specificity: Human Interleukin 6
• Formulation: Liquid tissue culture supernatant containing 15 mM sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: interleukin 6
• Database Link:
  Entrez Gene 3569 Human
  UniProt ID P05231
• Background: IL-6 is a multifunctional cytokine that is secreted by both lymphoid and non-lymphoid cells. It plays a key role in immune responses, hematopoiesis and is an important cytokine in cell proliferation and differentiation. It may also play an important role as an autocrine growth factor in metastatic prostate cancer. IL-6 has been reported to play a role in secretion or release of pituitary hormone in pituitary hormone secreting cells and adenomas. In addition, IL-6 has been suggested to have a trophic effect in nerve cells and to have a direct pathogenic role in CNS disorders. There are an increasing number of reports that cytokines of the IL-6 family play an important regulatory role in heart physiology.
• Synonyms: BSF-2; BSF2; CDF; HGF; HSF; IFNB2; IL-6; OTTHUMP00000158544