Aurora C (AURKC) Rabbit Polyclonal Antibody

CAT#: TA350902

Rabbit Polyclonal Anti-AURKC Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-5: Mouse testis tissue hela cells human liver cancer tissue A375 cells 293T cells Primary antibody: TA350902 (AURKC Antibody) at dilution 1/150 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350902 (AURKC Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA350902 (AURKC Antibody) at dilution 1/15, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse testis tissue and hela cells, human liver cancer and A375 cells, 293T cells
  IHC: 15-50
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human AURKC
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: aurora kinase C
• Database Link:
  NP_003151
  Entrez Gene 20871 MouseEntrez Gene 6795 Human
  UniProt ID Q9UQB9
• Background: This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
• Synonyms: AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13

Reference Data

• Protein Families: Druggable Genome, Protein Kinase