SIGLEC5 Rabbit Polyclonal Antibody
Frequently bought together (3)
Transient overexpression lysate of sialic acid binding Ig-like lectin 5 (SIGLEC5)
USD 436.00
Recombinant protein of human sialic acid binding Ig-like lectin 5 (SIGLEC5), 20 µg
USD 867.00
Other products for "SIGLEC5"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 200-1000 WB positive control: Mouse liver tissue IHC: 50-200 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human SIGLEC5 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 61 kDa |
Gene Name | sialic acid binding Ig like lectin 5 |
Database Link | |
Background | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion |
Synonyms | CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Documents
Product Manuals |
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