GRP94 (HSP90B1) Rabbit Polyclonal Antibody

CAT#: TA347766

Rabbit Polyclonal Anti-GRP94 Antibody

Product Images

Western blot analysis on SKOV3 cell lysate using GRP94 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-GRP94 Antibody: A synthesized peptide derived from human GRP94
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 92 kDa
• Gene Name: heat shock protein 90kDa beta family member 1
• Database Link:
  NP_003290
  Entrez Gene 22027 MouseEntrez Gene 7184 Human
  UniProt ID P14625
• Background: GRP94 Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5.
• Synonyms: ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
• Note: GRP94 Antibody detects endogenous levels of GRP94

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer