HDAC3 Rabbit Polyclonal Antibody

CAT#: TA347765

Rabbit Polyclonal Anti-HDAC3 Antibody

Product Images

Western blot analysis on NIH-3T3 cell lysate using HDAC3 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-HDAC3 Antibody: A synthesized peptide derived from human HDAC3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: histone deacetylase 3
• Database Link:
  NP_003874
  Entrez Gene 15183 MouseEntrez Gene 84578 RatEntrez Gene 8841 Human
  UniProt ID O15379
• Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
• Synonyms: HD3; RPD3; RPD3-2
• Note: HDAC3 Antibody detects endogenous levels of HDAC3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors