Ephrin A5 (EFNA5) Rabbit Polyclonal Antibody

CAT#: TA347661

Rabbit Polyclonal Anti-EFNA5 Antibody

Product Images

Western blot analysis on HeLa cell lysate using EFNA5 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-EFNA5 Antibody: A synthesized peptide derived from human EFNA5
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: ephrin A5
• Database Link:
  NP_001953
  Entrez Gene 13640 MouseEntrez Gene 116683 RatEntrez Gene 1946 Human
  UniProt ID P52803
• Background: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands
• Synonyms: AF1; EFL5; EPLG7; GLC1M; LERK7; RAGS
• Note: EFNA5 Antibody detects endogenous levels of EFNA5

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance