Claudin 3 (CLDN3) Rabbit Polyclonal Antibody

CAT#: TA347353

Rabbit Polyclonal Anti-Claudin 3 Antibody

Product Images

Western blot analysis on COLO205 cell lysate using Claudin 3 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Claudin 3 Antibody: A synthesized peptide derived from human Claudin 3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, sodium azide and glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: claudin 3
• Database Link:
  NP_001297
  Entrez Gene 12739 MouseEntrez Gene 65130 RatEntrez Gene 1365 Human
  UniProt ID O15551
• Background: claudin 3 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
• Synonyms: C7orf1; CPE-R2; CPETR2; HRVP1; RVP1
• Note: Claudin 3 antibody detects endogenous levels of total Claudin 3

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction