IL17E (IL25) Mouse Monoclonal Antibody [Clone ID: 8B1]
Frequently bought together (3)
Purified recombinant protein of Homo sapiens interleukin 25 (IL25), transcript variant 2, 20 µg
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Specifications
Product Data | |
Clone Name | 8B1 |
Applications | FC, WB |
Recommended Dilution | Western Blot: 0.5-2ug/ml, Flow Cytometry: 1-2ug/ml |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1, kappa |
Clonality | Monoclonal |
Immunogen | Full-length human IL17E recombinant protein was used as the immunogen for this antibody. |
Formulation | PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | interleukin 25 |
Database Link | |
Background | As a member of the IL-17 family, IL-25 has been identified as a pro-inflammatory cytokine which is produced by Th17 effector cells thus enabling the TH17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis (1-3). IL-25 appears to stimulate IL-8 production and itself appears to be activated through IL-23, IL-6, and TGF-Beta (1). Studies of IL-25 expression and activation through NF-kB taken together with IL-17 production and Th17 polarization through TLR ligand activation further closely tie the IL-17 and Th17 family together with the TLR signaling network initiating and controlling immune responses (4-7). |
Synonyms | IL17E |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
Product Manuals |
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