NUR77 (NR4A1) Rabbit Polyclonal Antibody
Frequently bought together (2)
Purified recombinant protein of Homo sapiens nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1, 20 µg
USD 867.00
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Specifications
Product Data | |
Applications | ChIP, ICC/IF, IHC, IP, WB |
Recommended Dilution | Chromatin Immunoprecipitation (ChIP): 1:20-1:1000, Western Blot: 1:500-1:1000, Immunohistochemistry-Paraffin: 1:200, Chromatin Immunoprecipitation: 1:20-1:1000, Immunocytochemistry/ Immunofluorescence: 1:10-1:2000, Immunoprecipitation: 1:20-1:1000, Immunohistochemistry: 1:200 |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This antibody was developed against a synthetic peptide corresponding to aa 251-266 of human Nak1 (NP_775180). |
Formulation | PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | nuclear receptor subfamily 4 group A member 1 |
Database Link | |
Background | Nak1 is a member of the steroid/thyroid hormone receptor superfamily. The gene for Nak-1 is induced rapidly by androgens/growth factors and may have functions related to cell proliferation, differentiation and apoptosis (1). Liu et al (2) have demonstrated that mouse nur77 is necessary for induced apoptosis in T-cell hybridomas and can also be induced during early mitogenesis. Nak1 is a phosphoprotein and its size ranges from 67 kD to 88 kD, depending on post-translational modifications. |
Synonyms | GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3 |
Note | Chromatin Immunoprecipitation: See Lee et al (2009) Immunocytochemistry/Immunofluorescence: See Chintharlapalli et al (2005) Immunoprecipitation: See Ferlini et al (2009) |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | MAPK signaling pathway |
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