Kappa Opioid Receptor (OPRK1) Rabbit Polyclonal Antibody

CAT#: TA330000

Rabbit Polyclonal Anti-OPRK1 Antibody

Product Images

WB Suggested Anti-OPRK1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain

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  WB Suggested Anti-OPRK1 Antibody Titration: 1 ug/ml; Positive Control: HuFetal Kidney

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-OPRK1 antibody: synthetic peptide directed towards the N terminal of human OPRK1. Synthetic peptide located within the following region: DSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEP
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: opioid receptor kappa 1
• Database Link:
  NP_000903
  Entrez Gene 4986 Human
  UniProt ID P41145
• Background: OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.
• Synonyms: K-OR-1; KOR; KOR-1; OPRK
• Note: Immunogen sequence homology: Human: 100%; Guinea pig: 91%; Pig: 85%; Mouse: 84%

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction