TNFRSF14 Rabbit Polyclonal Antibody
Frequently bought together (3)
Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14)
USD 436.00
Recombinant protein of human tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), 20 µg
USD 867.00
Other products for "TNFRSF14"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-1:2000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human TNFRSF14 |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | tumor necrosis factor receptor superfamily member 14 |
Database Link | |
Background | The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes. |
Synonyms | ATAR; CD270; HVEA; HVEM; LIGHTR; TR2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
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