Kcna1 Mouse Monoclonal Antibody [Clone ID: S20-78]
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Specifications
Product Data | |
Clone Name | S20-78 |
Applications | IHC |
Recommended Dilution | WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Synthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG) |
Formulation | PBS pH7.4, 50% glycerol |
Concentration | lot specific |
Purification | Protein G Purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | potassium voltage-gated channel subfamily A member 1 |
Database Link | |
Background | Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene . It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion . The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel . |
Synonyms | AEMK; EA1; HBK1; HUK1; HUKI; Kv1.1; MBK1; MGC126782; MGC138385; MK1; RBK1 |
Note | ~85kDa (major: Mature glycosylation), ~65kDa (minor: immature glycosylation) |
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