BCR Rabbit Polyclonal Antibody

CAT#: TA325269

Rabbit Polyclonal Bcr (Tyr177) Antibody (Phospho-specific)

Product Images

Western blot analysis of Bcr phosphorylation expression in K562 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human Bcr around the phosphorylation site of Tyrosine 177
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 160 kDa
• Gene Name: BCR, RhoGEF and GTPase activating protein
• Database Link:
  NP_004318
  Entrez Gene 110279 MouseEntrez Gene 613 Human
  UniProt ID P11274
• Background: Bcr is a serine/threonine and GTPase-activating protein (GAP). breakpoint cluster region protein. GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.
• Synonyms: ALL; BCR1; CML; D22S11; D22S662; PHL

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Chronic myeloid leukemia, Pathways in cancer