SEMA3G Rabbit Polyclonal Antibody

CAT#: TA322270

Anti-SEMA3G Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA322270 (SEMA3G Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA322270 (SEMA3G Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA322270 (SEMA3G Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA322270 (SEMA3G Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colorectal cancer
  Predicted cell location: Secreted
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: semaphorin 3G
• Database Link:
  NP_064548
  Entrez Gene 56920 Human
  UniProt ID Q9NS98
• Background: Semaphorins?are a class of secreted and membrane?proteins?that act as?axonal?growth cone?guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric?receptor?complexes. They are usually cues to deflect axons from inappropriate regions; especially important in?neural system?development. The major class of proteins that act as their receptors are called?plexins.SEMA3G possesses anti-migration and anti-invasion ability. SEMA3G inhibited tumor cell migration and invasion; which may be obtained through cell autonomous or paracrine mechanisms; and SEMA3G is a potential target for antitumor migration and invasion.
• Synonyms: sem2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Axon guidance