Ku70 (XRCC6) Rabbit Polyclonal Antibody
Frequently bought together (3)
Transient overexpression lysate of X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6)
USD 436.00
Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), 20 µg
USD 867.00
Other products for "Ku70"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 10-50 Positive control: Human colon cancer Predicted cell location: Nucleus |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a C terminal 300 amino acids of human X-ray repair complementing defective repair in Chinese hamster cells 6 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | X-ray repair complementing defective repair in Chinese hamster cells 6 |
Database Link | |
Background | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair; transposition; and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |
Synonyms | CTC75; CTCBF; G22P1; KU70; ML8; TLAA |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Non-homologous end-joining |
Documents
Product Manuals |
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