ZMYM2 Rabbit Polyclonal Antibody

CAT#: TA319739

Rabbit Polyclonal ZMYM2 Antibody

Product Images

Western blot analysis of ZMYM2 in EL4 cell lysate with ZMYM2 antibody at (A) 0.125 and (B) 0.25 ug/mL.

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  Immunofluorescence of ZMYM2 in HeLa cells with ZMYM2 antibody at 20 ug/mL.

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  Immunocytochemistry of ZMYM2 in HeLa cells with ZMYM2 antibody at 10 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0. 125 - 0.25 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ZMYM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM1.
• Formulation: ZMYM2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ZMYM2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: zinc finger MYM-type containing 2
• Database Link:
  NP_932072
  Entrez Gene 76007 MouseEntrez Gene 305913 RatEntrez Gene 7750 Human
  UniProt ID Q9UBW7
• Background: ZMYM2 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.
• Synonyms: FIM; MYM; RAMP; SCLL; ZNF198

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors