NT5C2 Rabbit Polyclonal Antibody

CAT#: TA308031

Rabbit Polyclonal antibody to NT5C2 (5'-nucleotidase, cytosolic II)

Product Images

Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA308031 diluted at 1:500.

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  Sample (30 ug whole cell lysate). A:H1299. B:HeLa S3. 7.5% SDS PAGE. TA308031 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded OVCA, using NT5C2 (TA308031) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Bovine, Rhesus Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 108 and 362 of NT5C2 (Uniprot ID#P49902)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 65 kDa
• Gene Name: 5'-nucleotidase, cytosolic II
• Database Link:
  NP_001127845
  Entrez Gene 76952 MouseEntrez Gene 22978 Human
  UniProt ID P49902
• Background: Purine 5-prime-nucleotidase (EC 3.1.3.5) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. The enzyme is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. [supplied by OMIM]
• Synonyms: cN-II; GMP; NT5B; PNT5; SPG45; SPG65
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%), Bovine (100%)

Reference Data

• Protein Pathways: Metabolic pathways, Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism